University of California, San Diego Main PageSailor Group HomeDepartment of Chemistry and Biochemistry, UCSD

Home Announcements Research People Publications Contact information

SAILOR RESEARCH GROUP >>RESEARCH >>Nano Imprints Frequently Asked Questions

NanoImprint FAQs
Can you explain a little further as to how the optical plastic would
measure strain on a joint or how far sutures have disolved? Would the sutures be made from optical plastic?
One of the polymers we have used is similar to that used in medical sutures, but it is also used in a variety of other in-vivo applications such as coatings for coronary artery stents, and as an implantable carrier for drugs. In these latter two applications, the polymer film is impregnated with a drug (such as a chronic pain medication, anti-cancer, anti-inflammatory or anti-rejection drug) and the whole thing is implanted into the body. As the polymer dissolves, the drug is released (usually over the space of several weeks). In the paper (Science 2003, 299, 2045-2047) we demonstrated two key milestones for these kinds of applications: first, that such a polymer can be imprinted with an optical nanostructure that gives it a color code, easily read through tissue using a simple flashlight-based spectrometer; and second, that the degradation of the color code provides a surrogate marker of the delivery of a drug (caffeine in our experiments).

How long might it be before the system is available to patients?
It is important to stress that we have only proven the principle in-vitro; the methodology needs to be validated in vivo before we can answer your question.

Designed by Andrea Tao.
Main address: Department of Chemistry, University of California, San Diego, 9500 Gilman Dr., La Jolla, CA 92093-0358 (858) 534-0227
Send questions, comments, and suggestions to: feedback@ucsd.edu.

Last modified Monday, February 17, 2003